Ethyl 2-(hydroxyimino)-2-(1H-imidazol-1-yl)acetate
Ethyl 2-(hydroxyimino)-2-(1H-imidazol-1-yl)acetate
CAS: 95080-92-5
Molecular Formula: C7H9N3O3
Ethyl 2-(hydroxyimino)-2-(1H-imidazol-1-yl)acetate - Names and Identifiers
Ethyl 2-(hydroxyimino)-2-(1H-imidazol-1-yl)acetate - Physico-chemical Properties
| Molecular Formula | C7H9N3O3 |
| Molar Mass | 183.16 |
| Melting Point | 142～144℃ |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| MDL | MFCD09027146 |
Ethyl 2-(hydroxyimino)-2-(1H-imidazol-1-yl)acetate - Introduction
Ethyl 2-(hydroxyimino)-2-(1H-imidazol-1-yl)acetate is an organic compound with the following properties:
1. Appearance: It is a colorless liquid.
2. Solubility: It can be dissolved in common organic solvents, such as ethanol and dimethylformamide.
3. Chemical properties: It is a compound containing ester and imine groups and is hydrophilic. It can be converted to the corresponding aldehydes and imines by hydrolysis under acidic conditions.
Ethyl 2-(hydroxyimino)-2-(1H-imidazol-1-yl)acetate is mainly used in organic synthesis, especially in the field of pharmaceutical and pesticide research and development. It is often used as a synthetic intermediate to participate in the synthesis of the corresponding target compounds. For example, it can be used to synthesize biologically active compounds, such as antibacterial agents and anti-tumor drugs.
The preparation method of Ethyl 2-(hydroxyimino)-2-(1H-imidazol-1-yl)acetate can be carried out by the following steps:
1. Get 2-(1H-imidazol-1-yl)acetic acid.
2. react with hydroxylamine to generate 2-(hydroxyimino)-2-(1H-imidazol-1-yl)acetic acid.
3. Esterification with ethanol to produce Ethyl 2-(hydroxyimino)-2-(1H-imidazol-1-yl)acetate.
Some safety information to note when using Ethyl 2-(hydroxyimino)-2-(1H-imidazol-1-yl)acetate:
1. Because it is an organic compound, contact with skin and eyes should be avoided. Wear appropriate protective gloves, glasses and protective clothing when using.
2. During the operation, a well-ventilated laboratory environment should be ensured to avoid inhaling its vapor.
3. When storing Ethyl 2-(hydroxyimino)-2-(1H-imidazol-1-yl)acetate, it should be stored in a closed container, away from fire and oxidant.
1. Appearance: It is a colorless liquid.
2. Solubility: It can be dissolved in common organic solvents, such as ethanol and dimethylformamide.
3. Chemical properties: It is a compound containing ester and imine groups and is hydrophilic. It can be converted to the corresponding aldehydes and imines by hydrolysis under acidic conditions.
Ethyl 2-(hydroxyimino)-2-(1H-imidazol-1-yl)acetate is mainly used in organic synthesis, especially in the field of pharmaceutical and pesticide research and development. It is often used as a synthetic intermediate to participate in the synthesis of the corresponding target compounds. For example, it can be used to synthesize biologically active compounds, such as antibacterial agents and anti-tumor drugs.
The preparation method of Ethyl 2-(hydroxyimino)-2-(1H-imidazol-1-yl)acetate can be carried out by the following steps:
1. Get 2-(1H-imidazol-1-yl)acetic acid.
2. react with hydroxylamine to generate 2-(hydroxyimino)-2-(1H-imidazol-1-yl)acetic acid.
3. Esterification with ethanol to produce Ethyl 2-(hydroxyimino)-2-(1H-imidazol-1-yl)acetate.
Some safety information to note when using Ethyl 2-(hydroxyimino)-2-(1H-imidazol-1-yl)acetate:
1. Because it is an organic compound, contact with skin and eyes should be avoided. Wear appropriate protective gloves, glasses and protective clothing when using.
2. During the operation, a well-ventilated laboratory environment should be ensured to avoid inhaling its vapor.
3. When storing Ethyl 2-(hydroxyimino)-2-(1H-imidazol-1-yl)acetate, it should be stored in a closed container, away from fire and oxidant.
Last Update：2024-04-09 21:21:28
